| Primary Identifier | MGI:5615964 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Lck |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| molecularNote | ENU mutagenesis induced a G to A transition at base pair 129,558,127 (v38) on chromosome 4, or base pair 15,515 in the GenBank genomic region NC_000070. The mutation corresponds to residue 149 in the NM_001162432 mRNA sequence in exon 2 of 13 total exons, or at position 191 bp of the NM_001162433 mRNA sequence in exon 2 of 13 total exons, or at position 1,050 of the NM_010693 mRNA sequence in exon 1 of 12 total exons. The mutation results in a cysteine to tyrosine substitution at position 31 (C31Y) in the protein isoform encoded by NM_001162432 and a cysteine to tyrosine substitution at position 25 (C25Y) in the protein isoforms encoded by NM_001162433 and NM_010693. |
