Primary Identifier | MGI:5618433 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Slc7a5 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting vector contains loxP sites flanking exon 1, including the initiation codon. An FRT-flanked neomycin resistance (neo) cassette fused to an internal ribosomal entry site (IRES) and a splice donor (SD) sequence, followed by a third loxP site, are placed downstream of exon 1. Flp-mediated recombination removed the FRT-flanked neo-IRES-SD cassette. |