Primary Identifier | MGI:5619347 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Rhot1 |
Transmission | Germline | Strain of Origin | C57BL/6 x 129/Sv |
Is Recombinase | false | Is Wild Type | false |
description | The ES cell used to generate this allele was derived from a segregating B6;129 background whereas that used to generate the tm2Jmsu allele was from a pure C57BL/6 background. The same construct was used in both targeted alleles. |
molecularNote | A loxP site, FRT-flanked neomycin resistance gene, exon 2, and a loxP site replaced exon 2. The FRT-flanked neomycin resistance gene was removed via Flp-mediated recombination leaving exon 2 flanked by loxP sites. |