Primary Identifier | MGI:5619128 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Mc4r |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU mutagenesis induced a T to A transversion at base pair 66,859,847 (v38) on chromosome 18, or base pair 641 in the GenBank genomic region NC_000084 encoding Mc4r. The mutation corresponds to residue 641 in the mRNA sequence NM_016977 within exon 1 of 1 total exons. The mutation results in a valine (V) to glutamic acid (E) substitution at position 65 (V65E) in the MC4R protein. |