|  Help  |  About  |  Contact Us

Allele : Nxn<em1(IMPC)J> nucleoredoxin; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:5620177 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Nxn
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project Nxn-6439J-FP22R was generated at The Jackson Laboratory by injecting Cas9 RNA and guide sequences GCGTCTAGGAATATTAGCGA, ACTCTGCAATTAATTTGGTT and TGACCCGGAAGGTAAGGCTT which resulted in a 5 bp deletion ATCGC in exon 2 beginning at Chromosome 11 negative strand position 76278553bp (GRCm38). This mutation is predicted to cause amino acid sequence changes after residue 133 and early truncation 21 amino acids later.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Nxn<em1J>,
  • Nxn<em1J>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories