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Allele : Ntrk1<tm1.1Jcar> neurotrophic tyrosine kinase, receptor, type 1; targeted mutation 1.1, Juan C Arevalo
Primary Identifier  MGI:5620208 Allele Type  Targeted
Attribute String  Not Specified Gene  Ntrk1
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A P782S mutation was introduced in exon 17 and an FRT flanked neo cassette was inserted in intron 17 via homologous recombination. Flp-mediated recombination removed the neo cassette. The expressed protein does not bind NEDD4L and is more active upon NGF binding.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • TrkAP782S,
  • TrkAP782S
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories





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