|  Help  |  About  |  Contact Us

Allele : Kit<tm1.1Gnf> KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1.1, Genomics Institute of the Novartis Research Foundation
Primary Identifier  MGI:5620943 Allele Type  Targeted
Attribute String  Not Specified Gene  Kit
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct introduced a C to T point mutation in exon 14 that results in the amino acid substitution of isoleucine for threonine at position 670 (T607I). Flp-mediated recombination removed an FRT-flanked neomycin resistance cassette with a 3' loxP site introduced downstream of the modified exon 14.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Kit<T670I>,
  • Kit<T670I>
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom