| Primary Identifier | MGI:5634713 | Allele Type | Transgenic |
| Attribute String | Constitutively active, Inducible, Inserted expressed sequence | Gene | Tg(CAG-Mtor*)#Atai |
| Strain of Origin | C57BL/6 | Induced With | rapamycin |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | This transgene consists of the ubiquitous CAG promoter, a floxed neo cassette, and the mutant rat Mtor kinase, which harbors four point mutations in the FKBP12-rapamycin binding and kinase domains (V2198A, L2216H, L2260P, and I2017T) with a FLAG tag at the N terminus. Excision of the floxed neo gene by cre recombinase induces active Mtor expression. The pound symbol (#) is used when a line is not specified and/or lines are pooled. |
