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Allele : Cdk6<tm1.1Mama> cyclin dependent kinase 6; targeted mutation 1.1, Marcos Malumbres
Primary Identifier  MGI:5635037 Allele Type  Targeted
Gene  Cdk6 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
description  ES cell = ESER1.56 (strain of origin not specified)
molecularNote  Exon 1 was replaced with a modified exon 1 in which nucleotide substitution (CGC to TGC) results in the amino acid substitution of cysteine for arginine at position 31 (R31C). Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of the modified exon.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Cdk6<R>,
  • Cdk6<R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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