|  Help  |  About  |  Contact Us

Allele : Fosb<tm3.1Yun> FBJ osteosarcoma oncogene B; targeted mutation 3.1, Yusaku Nakabeppu

Primary Identifier  MGI:5634958 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Fosb
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  Three bases (GAGGTGAGA->GAAGTTCGA) in the alternative splicing donor site and two bases (AGTGAA->TCTGAA) in the splice acceptor site were modified via homologous recombination to prevent expression of the long transcript while retaining expression of the shorter transcript. A floxed neo cassette was also inserted in intron 3. Cre mediated recombination removed the neo cassette. This allele lacks expression of the deltaFosb isoform.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • fosB<F>,
  • fosB<F>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele