Primary Identifier | MGI:5635436 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(TRATL3A6,TRBTL3A6)#Kito |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene expresses a Multiple Sclerosis patient-derived HLA DRB5*01:01-restricted myelin basic protein (83-99) specific TCR (TCR alpha and beta chains of the TL3A6 TCR). TL3A6 expresses Valpha9.2-Jalpha12-Calpha and Vbeta5.1-D-Jbeta1.2-Cbeta. The pound symbol (#) is used when line is not specified and/or lines are pooled. |