Primary Identifier | MGI:5636777 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(Scn10a-EGFP)ALmp |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains (from 5' to 3') the Na>V<1.8 putative promoter region (the 3.7 kbp sequence immediately upstream of a 24 kbp intron and transcriptional start site of the Scn10a gene) directing expression of an enhanced green fluorescent protein sequence (EGFP) followed by an SV40 early polyadenylation signal. Bright EGFP fluorescence is observed in peripheral sensory neurons, no EGFP expression is shown in sympathetic neurons. |