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Allele : Col2a1<tm2.1Mcali> collagen, type II, alpha 1; targeted mutation 2.1, Audrey McAlinden
Primary Identifier  MGI:5638780 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Col2a1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with one in which mutations (AGGTAT to CACTAC) altered the 5' splice site abolishing production of the type 2c isoform. Cre-mediated recombination removed the floxed neomycin resistance cassette inserted downstream of the modified exon 2.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Col2a1-mIIC,
  • Col2a1-mIIC
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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