Primary Identifier | MGI:5637368 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Vwf |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The majority of murine exon 28 was replaced with the human VWF A1 domain (amino acids 1240P through 1481G). In addition a floxed pGK-Neo cassette was inserted downstream of exon 28 which was removed via cre-mediated excision. |