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Allele : Magoh<tm1c(KOMP)Dlsi> mago homolog, exon junction complex core component; targeted mutation 1c, Debra L Silver

Primary Identifier  MGI:5638555 Allele Type  Targeted
Attribute String  Conditional ready Gene  Magoh
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
description  J:213515 used the KOMP vector PRPGS00072_A_G06 to create this allele.
molecularNote  The L1L2_Bact_P cassette was inserted at position 107737628 of Chromosome 4 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 2 at position 107738438. Exon 2 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp mediated recombination. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
  • mutations:
  • Insertion
  • synonyms:
  • Magoh<lox>,
  • Magoh<lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

7 Publication categories