Primary Identifier | MGI:5640779 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Rho*)STM2Rieke |
Strain of Origin | (C57BL/6J x DBA/2J)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene expresses mouse Rho in which phosphorylating serines 334, 338 and 343 have been converted to inactivating alanines. Threonine-associated phosphorylation sites (T336, T340 and T342) remain functional. An A337V mutation was introduced to confer a linear epitope for mAb3A6, that allows specific recognition of transgenic versus endogenous opsin. |