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Allele : Tg(Cx3cl1*)1Jung transgene insertion 1, Steffen Jung

Primary Identifier  MGI:5644036 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Cx3cl1*)1Jung
Strain of Origin  (BALB/c x C57BL/6)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a 120 kb BAC (#RP24147I16) containing the entire mouse Cx3cl1 (chemokine (C-X3-C motif) ligand 1) gene. This BAC was modified to place a nonsense mutation at amino acid 105, in exon 3, followed by a myc-tag. CCL22 and CCL17 sequences were removed from the BAC by restriction digest. The transgene encodes a secreted truncated protein lacking the mucin stalk.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • CX3CL1<105delta>,
  • CX3CL1<105delta>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories