Primary Identifier | MGI:5641188 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Rho*)TTM4Rieke |
Strain of Origin | (C57BL/6J x DBA/2J)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene expresses mouse Rho in which phosphorylating threonines 336, 340 and 342 have been converted to inactivating alanines. Serine-associated phosphorylation sites (S334, S338 and S343) remain functional. An A337V mutation was introduced to confer a linear epitope for mAb3A6, that allows specific recognition of transgenic versus endogenous opsin. |