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Allele : Tg(Rho*)TTM4Rieke transgene insertion TTM4, Fred Rieke

Primary Identifier  MGI:5641188 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Rho*)TTM4Rieke
Strain of Origin  (C57BL/6J x DBA/2J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene expresses mouse Rho in which phosphorylating threonines 336, 340 and 342 have been converted to inactivating alanines. Serine-associated phosphorylation sites (S334, S338 and S343) remain functional. An A337V mutation was introduced to confer a linear epitope for mAb3A6, that allows specific recognition of transgenic versus endogenous opsin.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Tg(Rho<T336A/T340A/T342A>),
  • Tg(Rho<T336A/T340A/T342A>)
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele