Primary Identifier | MGI:5644302 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(SFTPC-Tnf)2Pva |
Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human SFTPC promoter drives the expression of the full-length mouse Tnf, including the entire 3' UTR. Two lines, 2 and 10, were established. Line 2 with about 10 copies of the transgene was chosen as a representative line. Northern blots confirmed RNA expression in the lungs but not in other tissues (liver, spleen, heart, kidney, uterus, brain, large bowel, lymph nodes). |