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Allele : Casp3<m1H> caspase 3; mutation 1, MRC Mammalian Genetics Unit, Harwell

Primary Identifier  MGI:5646608 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Casp3
Strain of Origin  BALB/c Is Recombinase  false
Is Wild Type  false
description  The original mutation was identified from the MRC-Harwell's paired DNA-sperm library of ENU-mutagenised males.
molecularNote  The molecular lesion is a nucleotide substitution in codon 216 that introduces an MboII restriction site. This results in an Isoleucine to Phenylalanine change at amino acid 216 of the encoded protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Casp3<I216F>,
  • Casp3<I216F>,
  • Casp3<m1Bha>,
  • Casp3<m1Bha>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories