Primary Identifier | MGI:5646608 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Casp3 |
Strain of Origin | BALB/c | Is Recombinase | false |
Is Wild Type | false |
description | The original mutation was identified from the MRC-Harwell's paired DNA-sperm library of ENU-mutagenised males. |
molecularNote | The molecular lesion is a nucleotide substitution in codon 216 that introduces an MboII restriction site. This results in an Isoleucine to Phenylalanine change at amino acid 216 of the encoded protein. |