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Allele : Klhl3<tm1.1Esoh> kelch-like 3; targeted mutation 1.1, Eisei Sohara
Primary Identifier  MGI:5646378 Allele Type  Targeted
Attribute String  Not Specified Gene  Klhl3
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The point mutation R528H was introduced into exon 15 and a floxed pgk neo cassette was inserted into intron 14 via homologous recombination. Cre mediated recombination removed the neo cassette. The mutant protein shows impaired binding to WNK1 and WNK4.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • KLHL3<R528H>,
  • KLHL3<R528H>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories





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