Primary Identifier | MGI:5646253 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(TG-KCNIP3*)15Cnbc |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The cDNA encoding human KCNIP3 (DREAM) with two aminoacid substitutions at EFhands 2, 3 and 4 (EFmDREAM) was inserted downstream of the bovine Thyroglobulin promoter to direct expression in the thyroid gland. The amino acid substitutions rendered the mutant insensitive to Ca2+. |