| Primary Identifier | MGI:5647996 | Allele Type | Chemically induced (ENU) |
| Gene | b2b3121Clo | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | B2B/CvDC |
| description | Summative Diagnosis: Mutant Type 1: Cardiovascular phenotypes: outflow anomaly comprising of bicuspic aortic or pulmonary valves. Noncardiovascular phenotype: cleft palate, hypoplastic thymus, enlarged adrenal gland Mutant Type 2: Noncardiovascular phenotype: Hydrocephalus with possible cerebral arteriovenous malformation - (Vein of Galen) |
| molecularNote | This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. More than one mutation in this line results in a discernible phenotype in a homozygous recessive screen. At least two segregating phenotype groups are identified. See Wrnb2b3121.1Clo and b2b3121.2Clo. |
