Primary Identifier | MGI:5647997 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Cdh5 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A T-to-C mutation at codon 685 (creating a p.Tyr685Phe amino-acid change) was introduced into exon 12 and a floxed neomycin resistance gene cassette was inserted into intron 12. Cre-mediated recombination removed the neo cassette. |