| Primary Identifier | MGI:5648245 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(IRBP-HEL)1Rc |
| Strain of Origin | C57BL/6 or CBA/CaJ | Is Recombinase | false |
| Is Wild Type | false |
| description | The transgene was microinjected into fertilized oocytes from a cross of CBA/CaJ and C57BL/6 mice. |
| molecularNote | These transgenic mice express hen egg lysozyme (HEL) in retinal photoreceptor cells. The expression construct comprised an extracellular lysozyme domain and transmembrane region derived from the MHC class I molecule H-2Kb under the control of the human IRBP promoter. Several lines were generated, and one transgenic line was selected for detailed analysis. |
