| Primary Identifier | MGI:5648248 | Allele Type | Chemically induced (ENU) |
| Gene | Dnah5 | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | B2B/CvDC |
| description | Summative Diagnosis: Cardiovascular phenotypes: Dextrocardia, complex congenital heart defect associated with heterotaxy. Noncardiovascular phenotype: Visceral organ situs anomalies. |
| molecularNote | This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is an A to T substitution at coding nucleotide 6766 in exon 41 of the cDNA (c.6766A>T, NM_133365). This changes the methionine residue to leucine at position 2256 of the encoded protein (p.M2256L). |
