| Primary Identifier | MGI:5648077 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Cnp-TVA,-lacZ)B8Ubc |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| description | All were phenotypically normal, viable and fertile. |
| molecularNote | The transgenic construct contained the entire mouse Cnp promoter region coupled to the 800-bp quail cDNA encoding the glycosylphosphatidylinositol-linked form of TVA (CD320 or Tv-a) gene, the receptor for avian retrovirus ALV, subgroup A (ALV-A), followed by an IRES (internal ribosomal entry site) sequence and the lacZ gene. Pronuclear injection generated three chimera founders with germ-line transmission (A7, B8 and C16). After initial characterization for expression of TVA the B8 line was selected for further breeding. |
