| Primary Identifier | MGI:5649285 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Kras |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site flanked hygromycin resistance gene and STOP cassette was inserted 100 bp upstream of a Kras mutagenized exon 2 in which valine codon 14 (GTA) was changed to isoleucine (ATA) (p.V14I). Cre-mediated recombination in the germline removed the floxed LSL cassette, allowing expression of the mutant allele. |
