| Primary Identifier | MGI:5662266 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Cyp17a1-NGF)2456Oje |
| Strain of Origin | (C57BL/6J x DBA/2J)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The human NGF gene is targeted to thecal-interstitial cells by the mouse 17alpha-hydroxylase promoter. RNase protection assays confirmed ovarian mRNA expression and to a much lesser extent, expression in the adrenal gland, in the kidney and the liver.Two lines, 2380 and 2456, were generated and exhibited similar phenotypes. Line 2456 was studied further. |
