| Primary Identifier | MGI:5648836 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sik1 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted between exons 1 and 2. An FRT-flanked neomycin resistance cassette with a loxP site was inserted between exons 7 and 8. Flp-mediated recombination remove the selection cassette. Cre-mediated recombination removed exons 2 through 7. Western blot analysis confirmed the absence of protein expression in primary hepatocytes. |
