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Allele : Hmox1<tm1.1Hes> heme oxygenase 1; targeted mutation 1.1, Harald Esterbauer

Primary Identifier	MGI:5649369	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Hmox1
Transmission	Germline	Strain of Origin	C57BL/6N
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 2 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
HO-1<fl>,
HO-1<fl>

earliestPublication:
Jais A, et al. (2014) Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man. Cell 158(1):25-40

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

13 Publication categories

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