| Primary Identifier | MGI:5662369 | Allele Type | Targeted |
| Attribute String | Inducible, Null/knockout, Recombinase | Gene | Ddr2 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | Part of exon 3 was replaced with two mutated mouse estrogen receptors that sequester cre to the cytoplasm, polyadenylation sequence and an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. Western blot analysis confirmed the absence of protein expression in cultured cardiac fibroblasts. Only low expression of the modified cre product was detected. |
