| Primary Identifier | MGI:5693898 | Allele Type | Transgenic |
| Attribute String | Transactivator | Gene | Tg(NEFH-tTA)8Vle |
| Strain of Origin | (C57BL/6J x C3H/HeJ)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The construct consists of ~18 kbp of the human neurofilament heavy polypeptide promoter (NEFH; from BAC RP11-91J21) upstream of the tetracycline-regulated transactivator gene (tTA or "Tet-Off"), followed by a polyA signal. Founder line 8 has its highest tTA expression in developmental late stage of the cortex, cerebellum and hippocampus, with expression also observed in olfactory bulb and in the rest of the brain. |
