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Allele : Ofcc1<tm1.2Tohn> orofacial cleft 1 candidate 1; targeted mutation 1.2, Tetsuo Ohnishi
Primary Identifier  MGI:5693944 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ofcc1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 3 and 4. RT-PCR confirmed the absence of all three transcript variants in whole brain and trunk from E14.5 embryos.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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