| Primary Identifier | MGI:5694812 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Kcnmb2 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert a loxP site upstream of exon 1 and a second loxP site downstream of exon 1 followed by an FRT-flanked neomycin resistance (neo) cassette and a third loxP site downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. Immunoprecipitation of cerebellum, adrenal medulla and cerebral cortex tissues confirmed that no protein was expressed in mutant mice. |
