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Allele : Kcnmb2<tm1.2Clin> potassium large conductance calcium-activated channel, subfamily M, beta member 2; targeted mutation 1.2, Christopher J Lingle

Primary Identifier  MGI:5694812 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnmb2
Transmission  Germline Strain of Origin  C57BL/6NTac-Tg(HBB-lacZ)ALey/Ley
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a loxP site upstream of exon 1 and a second loxP site downstream of exon 1 followed by an FRT-flanked neomycin resistance (neo) cassette and a third loxP site downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. Immunoprecipitation of cerebellum, adrenal medulla and cerebral cortex tissues confirmed that no protein was expressed in mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • beta2 KO,
  • beta2 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele