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Allele : Spns2<tm1Tni> SPNS lysolipid transporter 2, sphingosine-1-phosphate; targeted mutation 1, Tsuyoshi Nishi

Primary Identifier  MGI:5694845 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Spns2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ reporter gene and neomycin resistance cassette replaced part of exon 6 and exon 7, encoding the Arg200 that is essential for the S1P export activity. RT-PCR confirmed the absence of protein expression in the brain, liver, small intestine and stomach.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele