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Allele : Ppox<tm1.1Had> protoporphyrinogen oxidase; targeted mutation 1.1, Harry A Dailey

Primary Identifier  MGI:5697201 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph Gene  Ppox
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A single codon was mutagenized to replace the arginine at amino acid 59 with tryptophan, mimicking the predominant variegate porphyria mutation in the South African population. Cre-mediated recombination was used to delete the loxP flanked neomycin selection cassette that had been inserted into intron 2.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • R59W/lox,
  • VP/lox,
  • R59W/lox,
  • VP/lox
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories