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Allele : Tg(CD2-Tbx21)#Staka transgene insertion, Satoru Takahashi

Primary Identifier  MGI:5699426 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(CD2-Tbx21)#Staka
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A full-length, 2.5-kb mouse Tbx21 cDNA was inserted into the VA CD2 expression vector between, 5', the promoter, ATG-free mutant first exon and first intron of the human CD2 gene and 3', also from the CD2 gene, ~500 bp of 3' untranslated and flanking DNA including two polyadenylation signals and the 3' locus control region. A lacZ reporter gene was shown to be expressed from this vector in mature peripheral CD4+CD8- and CD4-CD8+ SP T lymphocytes and in peripheral CD4-CD8- DN T cells.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories