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Allele : Tg(Plp1-HTT*150Q)4aXjl transgene insertion 4a, Xiao-Jiang Li
Primary Identifier  MGI:5700344 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Plp1-HTT*150Q)4aXjl
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Expression of a cDNA encoding N-terminal human HTT (amino acids 1-212) containing 150 glutamines in the repeat region (150Q) is under the control of the oligodendrocyte specific murine Plp1 promoter. Western blot confirmed formation of aggregated HTT in the brain and selective expression in the brain stem, striatum, and corpus callosum.
  • mutations:
  • Insertion
  • synonyms:
  • PLP-150Q,
  • PLP-150Q
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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