| Primary Identifier | MGI:5700377 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Alk |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Two exons encoding the juxtamembrane domain and N-terminal portion of the kinase domain of Alk (exons 20 and 21, respectively) were replaced by a neomycin expression cassette. Western blot analysis confirmed loss of full-length protein in the striatum (nucleus accumbens) of homozygous mutant mice. |
