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Allele : Lepr<tm3.2Rck> leptin receptor; targeted mutation 3.2, Jeffrey M Friedman

Primary Identifier  MGI:5698840 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Lepr
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Two loxP sites were inserted upstream and downstream of the coding region of 19a. A PGK-Neo cassette, flanked by two FRT sites was inserted upstream of 19a in intron 18 next to the loxP site. The neomycin selection cassette was removed via Flp-mediated recombination. Exon 19a was deleted by Cre-mediated recombination.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • ObRa KO,
  • ObRa KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories