Primary Identifier | MGI:5700640 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence, Reporter | Gene | Tg(Sox2-Bgeo)1Skn |
Strain of Origin | C57BL/6 or DBA/2 | Is Recombinase | false |
Is Wild Type | false |
description | Transgenic founder mice were generated by pronuclear microinjection of (C57BL/6 x DBA/2)F2 zygotes, derived from crosses between superovulated (C57BL/6 x DBA/2)F1 (B6D2F1) females and B6D2F1 males. |
molecularNote | Expression of the E. coli beta-galactosidase/neomycin phosphotransferase (betageo) fusion gene is driven by regulatory elements of the mouse Sox2 gene that are present within 5.7 kb upstream of the unique Not1 site in the 5' untranslated region (5'-UTR). The sequence contains Sox2 telencephalon enhancer
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