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Allele : Tg(Sox2-Bgeo)1Skn transgene insertion 1, Silvia K Nicolis

Primary Identifier  MGI:5700640 Allele Type  Transgenic
Attribute String  Inserted expressed sequence, Reporter Gene  Tg(Sox2-Bgeo)1Skn
Strain of Origin  C57BL/6 or DBA/2 Is Recombinase  false
Is Wild Type  false
description  Transgenic founder mice were generated by pronuclear microinjection of (C57BL/6 x DBA/2)F2 zygotes, derived from crosses between superovulated (C57BL/6 x DBA/2)F1 (B6D2F1) females and B6D2F1 males.
molecularNote  Expression of the E. coli beta-galactosidase/neomycin phosphotransferase (betageo) fusion gene is driven by regulatory elements of the mouse Sox2 gene that are present within 5.7 kb upstream of the unique Not1 site in the 5' untranslated region (5'-UTR). The sequence contains Sox2 telencephalon enhancer function showMoreInlineList(listDiv) { jQuery(listDiv + ' ul li').each(function(index) { if (!jQuery(this).is(":visible")) { jQuery(this).show(); } }); jQuery(listDiv + ' ul li.show-more').hide(); } function applyShowMoreInlineList(listDiv, listLength) { jQuery(listDiv + ' ul li').each(function(index) { listLength -= jQuery(this).text().length; if (listLength <= 0) { jQuery(this).hide(); } }); if (listLength <= 0) { jQuery('
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    • mutations:
    • Insertion
    • synonyms:
    • Sox2 beta-geo telencephalic transgene,
    • Sox2 beta-geo telencephalic transgene,
    • 5.7 kb Sox2 transgene,
    • 5.7 kb Sox2 transgene
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    1 Feature

    Trail: Allele

    Genome

    0 Expresses

    0 Mutation Involves

    Phenotype

    Mouse alleles --> Mammalian phenotypes (MP terms)

     

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    Trail: Allele

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    3 Publication categories

    Trail: Allele