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Allele : Tg(SOD1*H46R*C111S)PAra transgene insertion P, Toshiyuki Araki

Primary Identifier  MGI:5699338 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(SOD1*H46R*C111S)PAra
Strain of Origin  (C57BL/6 x DBA/2)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A 12 kb genomic fragment containing the entire human SOD1 gene was mutated so that the histidine residue at position 46 was replaced by arginine and the cysteine residue at position 111 was replaced by serine. Five lines were established, including lines N, P, and Q. This line has 24-36 copy numbers of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • H46R/C111S (P),
  • H46R/C111S (P)
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories