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Allele : Ctsd<tm1.1Thre> cathepsin D; targeted mutation 1.1, Thomas Reinheckel

Primary Identifier	MGI:5702318	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Ctsd
Transmission	Germline	Strain of Origin	C57BL/6N
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting vector containing a loxP-flanked exon 2 of and an FRT-flanked puromycin selection cassette was intregrated into the locus by homologous recombination. Subsequently, the selection cassette was removed by flpe recombination.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Ctsd<flox>,
Ctsd<flox>

earliestPublication:
Ketscher A, et al. (2016) Neuroectoderm-specific deletion of cathepsin D in mice models human inherited neuronal ceroid lipofuscinosis type 10. Biochimie 122:219-26

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

7 Publication categories

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