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Allele : Gt(ROSA)26Sor<tm1(GNAQ*)Cvrk> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Catherine D Van Raamsdonk
Primary Identifier  MGI:5702870 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed with a minimal adenovirus type 2 major late splice acceptor, a loxP-flanked Neo-STOP cassette, a cDNA sequence encoding human GNAQ* (a mutant form of GNAQ rendered constitutively active by substitution of Glutamine 209 for Leucine (Q209L), and a bovine growth hormone polyadenylation signal.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm1(GNAQ*)Cvr>,
  • Rosa26-fs-GNAQ-Q209L,
  • Gt(ROSA)26Sor<tm1(GNAQ*)Cvr>,
  • Rosa26-fs-GNAQ-Q209L
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

6 Carried By

0 Driven By

8 Publication categories





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