| Primary Identifier | MGI:5704099 | Allele Type | Targeted |
| Attribute String | Conditional ready, Hypomorph | Gene | Ube3a |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin-stop cassette flanked by loxP sites was inserted into intron 3 via homologous recombination. Cre-mediated recombination can be used to reinstate gene expression. Western blot analysis of hippocampus, cortex, and cerebellum in mice with a maternally inherited allele show a severe decrease in protein levels. |